Supercharging Dietary supplements — The Energy of Nutraceutical DMSO Combos
During the last yr, I’ve labored to convey the general public’s consideration to dimethyl sulfoxide (DMSO) a forgotten pure remedy which quickly treats a variety of situations and that many research have proven could be very protected (offered it is used appropriately) and, most significantly (due to the 1994 DSHEA Act which legalized all pure therapies)1 is now available.
Since I imagine DMSO has immense potential to supply the medical group and particular person sufferers, I’ve diligently labored to compile proof that greatest helps its rediscovery. As such, all through this sequence, I’ve introduced over a thousand research that DMSO successfully treats:
• Strokes, paralysis, and plenty of different neurological or circulatory issues (mentioned right here).
• Persistent ache and tissue accidents, reminiscent of sprains, burns and non-healing wounds (mentioned right here).
• Quite a few autoimmune and contractile issues (mentioned right here).
• Head situations, reminiscent of tinnitus, imaginative and prescient loss, dental issues, and sinusitis (mentioned right here).
• Inside organ ailments, reminiscent of pancreatitis, infertility, liver cirrhosis, and endometriosis (mentioned right here).
• Pores and skin situations, reminiscent of varicose veins, pimples, hair loss, ulcers, and pores and skin most cancers (mentioned right here).
• Many various cancers (mentioned right here).
• Lung issues, together with bronchial asthma, COPD, pulmonary fibrosis, and cystic fibrosis (mentioned right here).
• Gastrointestinal issues, reminiscent of Crohn’s illness, ulcerative colitis, diverticulitis, peptic ulcers, cirrhosis, and gastritis (mentioned right here).
• Infections, together with persistent bacterial infections, herpes, and shingles (mentioned right here).
DMSO Mixture Therapies
DMSO’s skill to deal with a variety of diseases outcomes from its having a wide range of extremely uncommon properties that seem to deal with the basis causes of illness (e.g., it significantly improves circulation). One in all DMSO’s most noteworthy properties is its skill to boost the results of different substances, which in lots of circumstances makes it doable to surmount main dilemmas historically seen with these therapies.
DMSO’s distinctive skill to operate as a automobile is because of the truth that it could actually move by organic membranes with out damaging them,2 so as soon as it contacts the pores and skin, it quickly spreads all through the physique.3 On the identical time, concurrently it readily dissolves most substances and is ready to convey them with it into the physique. That is very helpful because it lets you:
• Apply a medicine topically or orally that will usually require an IV or injection.
• Make medication grow to be way more potent and capable of deal with situations that in any other case won’t reply to (e.g., these mixtures can penetrate and deal with antibiotic-resistant micro organism or chemotherapy-resistant cancers).
• Permit decrease doses of a drug for use, which are sometimes a lot much less poisonous and in lots of circumstances, counteract the toxicity of the blended remedy (as DMSO protects tissue from damage) — all of which make it extremely helpful for decreasing the hurt of chemotherapy.
Observe: Whereas DMSO can’t be patented, mixtures can. As such, whereas DMSO alone is “unsafe,” “ineffective,” and “unproven,” many “protected and efficient” DMSO pharmaceutical mixtures exist, together with many accredited by the FDA.
Nutraceutical Mixture Research
A big quantity of scientific literature exists on DMSO being utilized in mixture with pharmaceutical medication, and plenty of accredited DMSO merchandise additionally incorporate pure brokers reminiscent of menthol, camphor, lavandin, lavender oil, coriander oil, arnica, and capsicum. Many pure brokers, together with quite a few nutraceuticals, have additionally been repeatedly proven to synergistically mix with DMSO in lots of situations. DMSO, for instance, potentiates many aspects of vitamin C:
• A 2022 randomized trial of 25 sufferers (with 28 confirmed basal cell cancers),4 investigators discovered that when topical vitamin C was mixed with DMSO after 8 weeks, 86.7% cancers had fully disappeared, whereas with imiquimod (a standard topical pores and skin most cancers remedy with unwanted effects), solely 57.1% had disappeared (and extra unwanted effects occurred).
• DMSO and vitamin C (together with a number of different brokers reminiscent of glutamine) had been proven to guard the jejunal (intestinal) lining of horses from its blood provide being quickly minimize off.5
• Sjogren’s syndrome is kind of tough to deal with. In a single examine, DMSO alone offered vital enchancment, which was additional enhanced by the addition of vitamin C.6
DMSO has additionally been repeatedly proven to mix with the B nutritional vitamins synergistically. For instance, scleroderma is a extreme and continuously terminal dysfunction DMSO has repeatedly demonstrated exceptional outcomes for and vitamin B3 has been repeatedly proven to considerably improve the crucial blood circulation DMSO restores in these sufferers.7,8
Likewise, DMSO, vitamin B5, and insulin safely handled 42 sufferers ages 23 to 62 with persistent parenchymatous parotitis.9
Many research have additionally proven that vitamin E enhances DMSO’s skill to stop and heal tissue damage. This contains the tissue dying which follows chemotherapy brokers leaking into tissues,10,11,12,13 the lung damage, and life-threatening fluid accumulation throughout ARDS (an sickness that generally requires air flow)14,15,16 and free radical injury on account of radiation publicity.17,18 Different therapeutic antioxidants have additionally been proven to synergistically mix with DMSO:
• CoQ10 DMSO mixtures healed radiation accidents.19
• Alpha lipoic acid DMSO mixtures protected rat testes from having their blood provide minimize off by decreasing oxidative stress.20
• DMSO prevented 43% of sheep from dying from an in any other case all the time deadly smoke inhalation publicity, and when mixed with N-acetylcysteine (NAC), the survival charge doubled (to 86% surviving).21
• NAC additionally enhanced DMSO’s skill to guard kidneys after their blood provide was minimize off.22
• DMSO and linetol (a flaxseed focus with anti-inflammatory, regenerative, and wound-healing properties) successfully handled burns.23 Likewise, a DMSO collagen mixture did in order properly.24
• Alone, a Brazilian inexperienced propolis improved surgical wound therapeutic (and lowered irritation) by 40%,25 whereas together with DMSO, improved it by 50%, together with eliminating the necessity for antibiotics or inflammatory medicines.
• Following colon surgical procedure (the place a bit was eliminated and every finish was stitched collectively) DMSO and quercetin considerably improved therapeutic and the power of the ensuing scar.26
Observe: One Russian mixture remedy for treating trophic ulcers, wounds, burns, scars, and keloids makes use of 25% to 50% DMSO in a hyaluronic gel with collagen or MSM, ascorbic acid, and coenzyme Q10,27,28 whereas an analogous preparation, given as a suppository, was developed for rectal fissures.29
Different potent pure therapies have additionally demonstrated synergy with DMSO. For example, in 96 sufferers aged 51 to 89 with benign prostatic hyperplasia DMSO suppositories containing 30 mg prostatilen [prostate peptide] relieved infravesical obstruction signs, enhancing voiding issues in these with preliminary or average signs.30
Observe: DMSO has additionally been proven to boost the penetration of a transportation peptide into cells, permitting higher mobile distribution of it within the cytosol and nucleus.31,32
Therapeutic with Nutraceutical DMSO Combos
As there’s an nearly infinite variety of pure substances that may very well be mixed with DMSO, it has not been doable to analysis them.
Happily, the convenience, security, and efficacy of those mixtures have impressed many to take their well being into their very own palms and discover combining DMSO with many confirmed pure treatments and broadly used nutraceuticals — in lots of circumstances discovering their efficiency is enhanced, or therapeutic potentialities emerge which had been inconceivable with the nutraceutical alone. Key discoveries with these mixtures from the DMSO group embody:
• Vitamin C — Topical vitamin C and DMSO has been used to deal with pores and skin cancers (e.g., one reader replicated the outcomes of the examine I mentioned above33,34), to shrink overgrown scars (usually taking 6 to eight weeks) and for a wide range of localized infections (e.g., one reader used it to heal a longstanding tooth abscess35 and whereas one other handled a extreme eye an infection36).
In people with a depleted immune system and persistent infections, infusions (e.g., by slowly infusing vitamin C, hydrogen peroxide, and DMSO). I’ve additionally seen vitamin C utilized in formulations that promoted elevated wellness (e.g., much less ache or fatigue), but it surely’s unclear how a lot it was answerable for these results.
• Vitamin B12 — Like vitamin C, B12 typically requires injections to attain ample blood ranges, so having the ability to bypass that with topical DMSO is commonly extraordinarily helpful.
Many, in flip, have reported getting a speedy increase in vitality, normal power, happiness, and wellbeing from topical DMSO-B12 preparations, which significantly exceeds what oral B12 can present (and skips the hassles related to B12 pictures — significantly in youngsters).
Moreover, DMSO B12 drops can typically be helpful for nerve regeneration. This has been probably the most extensively explored for restoring misplaced odor (e.g., following a viral an infection), but it surely has additionally been used for tinnitus and listening to loss.
Observe: Whereas DMSO and B12 can be utilized alone, different issues may also be added. For instance, one German nasal spray (additionally used for nasal polyps, sinusitis, allergy symptoms, and jaw ache) accommodates H₂O₂, procaine, B12, DMSO in isotonic seawater.
• Methylsulfonylmethane (MSM) — MSM (oxidized DMSO) is the first metabolite of DMSO and shares many tissue therapeutic and anti inflammatory qualities with DMSO. As such is usually used as a partial substitute for DMSO for people who can’t tolerate the odor DMSO creates.
Curiously, when DMSO is mixed with MSM, its skill to heal and rebuild tissue (e.g., cartilage, scar tissue, wounds) and deal with joint points (e.g., scale back stiffness from osteoarthritis) is considerably enhanced, and I’ve come throughout quite a few studies of people with extreme knee or hip osteoarthritis having a dramatic enchancment in ache following ingesting this mixture.37
In some circumstances, that is additionally efficiently utilized in animals (e.g., one reader reported that mixture healed their horse’s knees38).
Moreover, DMSO-MSM mixtures are sometimes used to deal with different points. For instance, there’s additionally some knowledge exhibiting MSM drops assist eye points (e.g., cataracts and eye dryness),39 and I’ve often come throughout studies from readers of it eliminating them.40
Observe: Many different therapeutic potentialities exist for MSM (e.g., DMSO has been repeatedly proven to significantly improve the efficiency of pure most cancers therapies and research have proven that MSM has potent anticancer exercise towards breast most cancers and melanomas,41,42).
• Vitamin D and B12 — These have been used to enhance immune operate for preventing persistent infections (e.g., B12 helps the physique produce immune cells).
• Vitamin E — Topical preparations and suppositories have been efficiently used for prostate enlargement (mentioned additional right here). This mixture has additionally been used to help pores and skin therapeutic.
• B-complexes and multivitamins — These have been used for neuroprotection and symptom administration in Parkinson’s regimens.
• Glutathione and N-Acetylcysteine — Glutathione is significant for the physique however because it doesn’t soak up by ingestion, a wide range of approaches have been developed to extend it reminiscent of consuming its precursor N-Acetylcysteine, injecting it, ingesting liposomal glutathione (which within the manufacturers we checked didn’t improve blood glutathione ranges) or by nebulizing it (which in lots of circumstances produces dramatic outcomes for COPD, smoke inhalation accidents and wildfire toxicity).
Whereas many makes use of exist for these mixtures (e.g., each DMSO and NAC have been proven to deal with complicated regional ache syndrome), probably the most exceptional ones are seen when glutathione is combined with DMSO. This mixture, in flip continuously reverses or cures “incurable” lung situations (e.g., one reader shared {that a} cystic fibrosis affected person was capable of be taken off the transplant listing with this mixture, whereas many others shared DMSO handled their pulmonary fibrosis or COPD).
Observe: DMSO additionally continuously improves bronchial asthma.
• Coenzyme Q10 — That is typically used for mitochondrial help (e.g., for fatigue or neurodegenerative ailments) however stays comparatively unexplored by the DMSO group. Curiously, one reader reported doing analysis the place CoQ10 mixed with DMSO yielded very promising ends in treating spinal wire accidents in rats.43
• Tremendous oxide dismutase — Previously an ACAM doctor reported DMSO together with SOD handled cataracts and glaucoma (as did a later DMSO creator).44,45
Creating Your Personal House Cures
Regardless of having now reviewed hundreds of research with DMSO, there’s nonetheless a fantastic deal I don’t perceive concerning the substance, significantly the quite a few mixtures it may be used with. Happily, excluding circumstances the place there’s a exceptional and surprising synergy (e.g., DMSO and hematoxylin treating most cancers) these mixtures behave in a reasonably predictable sample.
So long as you might be aware to keep away from widespread points (e.g., utilizing an excessive amount of of an irritating or acidic substance like unbuffered vitamin C), these mixtures are comparatively protected and sometimes fairly efficient.
For instance, many people need options to chemical cosmetics that keep away from their toxicity and don’t irritate or deplete the pores and skin, however discover pure formulations typically don’t “do sufficient.” Nonetheless, when mixed with DMSO, these widespread components (e.g., lots of which I listed above) not solely grow to be more practical but in addition, in lots of circumstances, rejuvenate and restore the pores and skin, typically displaying exceptional antiaging results (e.g., pores and skin tightening).
As such, a variety of efficient beauty DMSO blends have been developed that not solely free customers from dangerous chemical formulations but in addition typically permit them to heal a wide range of difficult pores and skin points. Likewise, DMSO has been mixed with a wide range of different pure brokers, which have produced exceptional outcomes, in lots of circumstances making it doable to treatment incurable situations. These embody:
• Botanical treatments, lots of that are used for ache, arthritis, or accidents, are additionally used for difficult issues reminiscent of most cancers, dementia, and COVID-19.
• Important minerals, lots of that are used to deal with infections or heal accidents.
• Pure metabolites, lots of that are used to revive the physique (e.g., treating persistent fatigue or strengthening weakened tissue), typically operate as exceptional cosmetics that quickly rejuvenate the pores and skin.
• Amino acid mixtures reliably deal with Down Syndrome and studying disabilities. Extra neurotransmitter mixtures had been later found to assuage the nervous system, enhancing sleep and nervousness.
• Oxidative therapies (e.g., chlorine dioxide or hydrogen peroxide) have gotten way more potent for eliminating infections (e.g., Lyme or toenail fungus) when mixed with DMSO. They’re additionally continuously used to deal with most cancers efficiently.
• Hematoxylin and some different dyes have demonstrated vital anticancer exercise with DMSO.
• DMSO considerably improves the elimination of poisons from the physique by detoxing therapies (significantly steel chelating brokers).
Lastly, many different physique therapies (e.g., acupuncture, hypnosis, meditation, and therapeutic massage) grow to be considerably more practical when mixed with DMSO. As such, practitioners in components of Europe continuously mix the 2.
Conclusion
The exceptional potential of DMSO mixture therapies represents a paradigm shift in how we method pure therapeutic and wellness. What we have found by hundreds of research and numerous affected person experiences is that DMSO would not simply deal with signs — it seems to deal with basic therapeutic mechanisms on the mobile degree, making a basis for the physique’s personal restorative processes to flourish.
The great thing about these pure mixtures lies not solely of their therapeutic efficacy however of their accessibility. In contrast to complicated pharmaceutical interventions that require specialised medical services and in depth oversight, many of those DMSO mixtures might be safely ready and used at dwelling, empowering people to take an lively function in their very own well being journey.
Maybe most encouraging is the rising group of practitioners, researchers, and sufferers who’re documenting their successes with these therapies. From persistent ache aid to most cancers remedy, from wound therapeutic to neurological restoration, the constant studies of enchancment throughout such a large spectrum of situations counsel we’re witnessing the emergence of a very transformative method to medication.
The way forward for medication could be present in DMSO’s skill to unlock the therapeutic potential that has all the time existed inside nature — we merely wanted the best key to entry it. That key’s now in your palms.
Creator’s Observe: That is an abridged model of an extended article, which matches into a lot larger element on what every of the pure DMSO mixtures can do and find out how to put together them at dwelling. That article, together with assets and protocols for acquiring and utilizing DMSO, might be learn right here. Moreover, a companion article explaining how DMSO interacts with a variety of drugs and the synergistic pharmaceutical mixtures which were found might be learn right here.
A Observe from Dr. Mercola Concerning the Creator
A Midwestern Physician (AMD) is a board-certified doctor from the Midwest and a longtime reader of Mercola.com. I admire AMD’s distinctive perception on a variety of subjects and am grateful to share it. I additionally respect AMD’s want to stay nameless since AMD continues to be on the entrance traces treating sufferers. To seek out extra of AMD’s work, remember to take a look at The Forgotten Facet of Drugs on Substack.
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